Health Care

what is colorectal cancer screening: Weight Loss Reduces Risk

Weight Loss Reduces The Risk Of Growth In Colorectal Cancer or we have to know about what is colorectal cancer screening?, According to a recent study performed by researchers at the University of Maryland School of Medicine.

Obese and overweight adults who lose weight may have a lower risk of getting colorectal adenoma, a benign growth or polyp in the colon or rectum that can evolve to colorectal cancer, according to a new study published in JNCI Cancer Spectrum by Oxford University Press.

What is colorectal cancer screening?

Colorectal cancer is the third most frequent cancer in men and women in the United States, and the third greatest cause of cancer death.

Obesity has increased in the United States and around the world in the last 30 years, leading to an increase in the development of several chronic diseases.

Obesity has long been recognized as a risk factor for colorectal adenoma and cancer.

Overweight and obese patients are frequently advised by doctors to lose weight. Although weight loss is known to have some health benefits, the question of whether it can lessen the risk of colorectal adenoma has remained unanswered.

The majority of research have only looked at colorectal adenoma risk in connection to obesity or BMI at a single time point, with fewer examining the role of weight change.

Weight Loss Reduces The Risk Of Growth In Colorectal Cancer

The Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial used self-reported weight data to investigate weight change (including both weight gain and weight loss) during three periods of adulthood in association to colorectal adenoma.

From 1993 to 2001, the experiment enrolled 154,942 men and women in the United States, ranging in age from 55 to 74, in order to assess the efficacy of various screening procedures in reducing death from various malignancies.

Participants in the screening arm of the trial, who got a colorectal cancer screening test at baseline and again 3 or 5 years later, were used in this analysis.

Colorectal Cancer

Weight loss in adulthood (defined as loss greater than or equal to 1.1 pounds per 5 years) was associated with a 46 percent lower incidence of colorectal adenoma, according to the researchers.

This was especially true for those who were overweight or obese at the start. The researchers also discovered that weight gain in adulthood was linked to an increased risk of adenoma, especially if the gain was higher than 6.6 pounds in 5 years.

The findings for weight loss and increase appeared to be more pronounced in males than in women. The findings, according to the researchers, point to the relevance of maintaining a healthy weight throughout adulthood in preventing colorectal adenoma.

Adults who are overweight or obese may also be able to lower their chances of having colorectal adenoma.

“Our findings imply that preventing weight gain in adulthood may lessen the risk of acquiring a precancerous growth called a colon adenoma, which may reduce the risk of colorectal cancer,” said Kathryn Hughes Barry, the study’s senior author.

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“We would not promote weight loss for all adults based on our findings.” However, the findings show that individuals who are overweight or obese may benefit from weight loss.”

The researchers found that losing weight from early adulthood through late adulthood (up to the mid-70s) — at least 2 pounds per decade — lowered a person’s risk of acquiring precancerous growths, called adenomas, by 46%.

Colorectal Cancer

The findings of the study show that weight loss is beneficial for persons who are overweight or obese. Weight loss was associated with a more than 60% reduction in risk among individuals who were overweight or obese at the age of 20, but not with those who had a lower BMI at the age of 20.

Gaining weight, on the other hand, raised a person’s likelihood of acquiring colorectal adenomas over time. According to the study, adding 6 pounds or more every five years was linked to a 30% greater chance of this type of growth.

According to the Centers for Disease Control and Prevention, more than 73 percent of adults in the United States aged 20 and over are overweight or obese.

Obesity is a risk factor for colorectal adenomas and colorectal cancer, which is the third most frequent cancer in both men and women in the United States and the third largest cause of cancer-related death.

Overall, the death rate from colorectal cancer has reduced, owing to improved screening and earlier discovery, but it has risen in younger persons.

Previous study, according to Barry, has mostly focused on adenoma risk in relation to obesity or BMI at a single moment in time rather than throughout time.

The influence of weight alterations in adenoma risk has been studied in fewer research. The majority of these research focused on weight increase.

Colorectal Cancer


According to a recent study performed by researchers at the University of Maryland School of Medicine, weight loss for adults, particularly those who are overweight or obese, may lessen their chance of acquiring a type of polyp that can lead to colon cancer (UMSOM).

People May Ask

Does obesity increase risk of colon cancer?

Obese people are slightly (approximately 30%) more likely than normal-weight people to get colorectal cancer. In both men and women, a higher BMI is linked to an increased risk of colon and rectal cancers, but the increases are greater in men.

What role does weight play in cancer risk?

Obesity or being overweight is definitely connected to an increased risk of cancer. Excess body weight is considered to be responsible with roughly 11 percent of cancers in women and about 5% of cancers in men in the United States, as well as about 7% of all cancer deaths, according to studies from the American Cancer Society.

Does smoking cause colon cancer?

People who smoke have more colon polyps that are bigger and more numerous. According to studies, having a parent, sibling, or kid with colon cancer increases the risk of developing colon cancer.

What cancers cause you to gain weight?

Without a doubt. Breast cancer sufferers, We believe, make up the majority of those who seek our assistance with weight gain. Prostate cancer patients, as well as lymphoma, multiple myeloma, and chronic leukemia patients, acquire a lot of weight.


The opinions presented in this article should not be regarded as a replacement for medical advice. For more information, please contact your treating physician.

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