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Premature Menopause And Dementia For Women

According to preliminary research, women who reach Premature Menopause And Dementia before the age of 40 have a 35 percent higher risk of acquiring dementia later in life.

The study is being discussed at the American Heart Association’s annual gathering this week, although it has not yet been published. Researchers used health data from 153,291 women with just an average age of 60 who took part in the UK Biobank, a large biomedical directory in the United Kingdom, for the research.


Study examined at women who were diagnosed with it as well as changed for factors like their age during their last test, race, educational status, cigarette as well as alcohol use, body mass index, heart disease, diabetes, income, as well as physical activity levels.

Women who began menopause at the age of 52 or older, on the other hand, had dementia rates comparable to the general public.

This raises a number of concerns about the relationship between menopause and dementia.

Premature Menopause And Dementia

As per the American College of Obstetricians and Gynecologists, it is the time in the life once you usually stop having periods (ACOG). Your ovaries also stop producing oestrogen, a hormone that aids in the regulation of your menstrual cycle.

According to the Office on Women’s Health at the U.S. Department of Health and Human Services, menopause that occurs before the age of 40 is known as premature menopause (OWH). It is referred to as early menopause when it occurs between the ages of 40 and 45. Approximately 5% of women naturally experience early menopause. (According to the OWH, the average age of menopause is 52.)

Early menopause be linked to dementia

The researchers did not investigate the connection between Premature Menopause And Dementia in their study; they simply discovered the association. However, the American Heart Association stated in a press release that lower oestrogen levels associated with it may be a factor.

“We know that a lack of oestrogen over time increases oxidative stress, which may accelerate brain ageing and result in cognitive impairment,” said research co-author Wenting Hao, M.D., a PhD student at Shandong University in Jinan, China. (oxidative stress occurs when unstable atoms accumulate in your body and cause cell damage.)


The drop in oestrogen may also play a role, according to Lauren Streicher, M.D., clinical professor of obstetrics and gynaecology at Northwestern University Feinberg School of Medicine as well as author of Hot Flash Hell. “We surely know that when someone stops producing oestrogen, there are vascular variations,” she says.

“There could actually be less oxygen going to the brain, which could increase the risk of developing Premature Menopause And Dementia.” “It may not just be about reduced oestrogen,” she adds. There are many people who have low oestrogen levels and do not grow dementia.”

The findings are “not surprising,” according to Mary Jane Minkin, M.D., a clinical professor of obstetrics and gynaecology and reproductive sciences at Yale Medical School.

“We’ve known for years that women who go through menopause early and don’t use oestrogen replacement treatment have a noticeably higher risk of heart disease as well as dementia,” she says. “What is the significance of this link?” “We know from some experimental results that women who take oestrogen relatively early in menopause within 6 years of menopause—have less thickness of their carotid blood vessels than women who do not take oestrogen,” Dr. Minkin says. “Also, blood flow to the brain is adequate.”

Scott Kaiser, M.D., a board-certified geriatrician and Director of Geriatric Cognitive Health at Charity Saint John’s Health Center in Santa Monica, Calif., also notes that out women are more likely than men to get Alzheimers disease. “A lot of work has gone into trying to explain these sex-based variations, and this study provides some key insights and raises some crucial issues,” he says.

“There have been studies that suggest oestrogen may play a significant role in cognition as well as Alzheimer’s disease,” says Doug Scharre, M.D., a neurologist as well as Director of The Ohio State University Wexner Medical Center’s Center for Cognitive as well as Memory Disorders. He references a previous study that revealed that women who took oestrogen supplementation throughout it had a lower risk of Alzheimer’s disease than those who didn’t.

However, Amit Sachdev, M.D., medical director of Michigan State University’s department of neurology as well as ophthalmology, believes that additional research is needed before people jump to conclusions. He cautioned, “I would take this tendency with a grain of salt.” “It’s quite a jump from there to brain deterioration.”

Christine Greves, M.D., an ob/gyn at the Winnie Palmer Hospital for Women and Babies in Orlando, adds, “The truth is, nobody thinks.” “This doesn’t prove causality; it only shows that there is a connection.” There is a need for further research.”

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Lower your risk of Premature Menopause And Dementia

According to Dr. Sachdev, it is a complex disorder that can be caused by a variety of circumstances. As a result, he advises people to focus on their overall health in order to reduce their risk. He claims that “a physical health leads to a healthy brain.” “It’s great to have better overall health.”

“It’s critical for all of us to think about how we participate in that way of improving our brain health,” Dr. Kaiser adds, “but it’s particularly important for people with elevated risk, which might include women going through Premature Menopause And Dementia”

To reduce their risk, the US Department of Health and Human Services (HHS) suggests that people undertake the following:


If you’re going through it, though, Dr. Streicher suggests talking to your doctor about oestrogen supplementation, which can help you avoid a plethora of unpleasant side effects including hot flashes as well as possibly Premature Menopause And Dementia. “It’s so unjust that women are expected to just ‘tough it out’ and risk major health implications,” according to her.


The production of the female sex hormone oestrogen diminishes rapidly after it, as well as a woman’s periods end. While most women reach menopause in their early 50s, some do so sooner, either naturally or as a result of a medical illness or therapy including a hysterectomy (removal of the uterus).


What causes dementia in the first place?

Alzheimer’s disease is a common cause.

What is the distinction between dementia and Alzheimer’s disease?

Alzheimer’s disease is an unique degenerative brain illness that causes gradual deterioration in memory and cognitive function. Dementia is the term used to describe a combination of symptoms that negatively effect memory.

How long do dementia patients live?

A person with Alzheimer’s disease survives on average four to eight years following diagnosis, although it can last up to 20 years depending on other circumstances.

Can Dementia strike at any age?

It is more frequent in adults over 65, although it can also affect persons in their 30s, 40s, and 50s in some situations.

Is it common for someone with dementia to sleep a lot?

A person with dementia is likely to spend a significant amount of time sleeping, both during the day and at night, especially as the disease progresses.

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