Disease

New HIV Virus Transmission More severe and contagious

Researchers discovered that a New HIV Virus Transmission which is faster at progressing to severe disease and more contagious than other strains has been spreading in the Netherlands for decades.

The studies, which were reported on Thursday in the journal Science, show how HIV can change to cause more serious illnesses and faster transmission.

“Even after 100 years of infecting humans, HIV has the ability to evolve as well as change,” says Joel Wertheim, an associate professor who’s not involved in the study but wrote a commentary on the study results, which was also posted in Science on Thursday.

In the time of COVID mutations, the research acts as a reminder that viruses don’t always weaken over the duration. “The potential for viral mutation should never be underestimated,” Wertheim argues. “Let this study stand in sharp contrast to the idea that all viruses will eventually develop into benign forms.”

A contagious new discovery-New HIV Virus Transmission

A strange group of samples led to the finding of the HIV variant.

Chris Wymant, the report’s lead author as well as a senior researcher, observed something impressive in a database for the BEEHIVE proposal, which gathers HIV samples from Uganda as well as several European countries to help scientists know how well the virus is developing.

According to him, there was a recent cluster of 17 samples that revealed a lot of odd mutations, 15 of which originated from the Netherlands.

Wymant and his co-authors were curious, so they looked into another Dutch study that had more information. They uncovered a total of 109 persons with HIV Variant who had no idea they had it, dating back to 1992. According to Wymant, the variety first appeared in the late 1980s, gained traction about 2000, and then slowed down around 2010.

HIV

The viral load of people with this variation is three to four times higher than it is for HIV patients. According to Wymant, this property causes the virus to progress twice as quickly into serious sickness, as well as making it more contagious.

The good news is that existing drugs may effectively cure even the most virulent varieties, such as this one, minimizing transmission and the risk of severe sickness, according to him.

“There’s no need to be concerned,” Wymant argues. “It reacts to treatment in the same way as HIV does.”

He goes on to say that no particular therapies are required for this variety. It shows no symptoms of drug resistance, which several HIV variants do. However, because the variation spreads swiftly, people must undergo treatment as soon as possible.

Read Also-Small Period Changes After COVID Vaccine Seen To Be Short-Lived: UK Expert

HIV

How can HIV variants be slowed down?

Adeeba Kamarulzaman, president of the International AIDS Society and professor of medicine at the University of Malaya, who was not involved in the study, believes it was “nicely done” as well as “well-designed.”

She also points out that it helps to solve a crucial topic in HIV research. Researchers have wondered if how people’s immune systems react to the virus causes them to become worse or more infectious. Individual reactions are part of it, but not all, according to the research. It’s also possible if a virus changes to produce more severe sickness and spread more quickly.

A mutation like this, Kamarulzaman says, might occur elsewhere. If a large proportion of HIV patients in a given location have this mutation but aren’t taking treatment, she says, “you’re going to have a lot more patients with the severe disease a lot faster.”

“Early tests or regular testing and prompt beginning of medication is the way to go,” she explains, to avoid this. The goal isn’t to find a specific variety, but to diagnose new HIV variant cases as quickly as possible so that treatment can begin. However, certain countries are still having difficulty doing so, and they require additional assistance, she adds.

HIV

That’s how, in the Netherlands, this version slowly slowed down before experts even noticed it.

“Even though we didn’t know existed, the healthcare involvement that has been turned out and expanded in the Netherlands over last years or so — enhancing access to treatments, getting more people evaluated as quickly as possible, obtaining them on treatment as quickly as possible — has aided reduce the numbers of HIV variant,” Wymant says.

Rapid treatment also helps to reduce viral evolution, reducing the likelihood of variations like this emerging.

“This does not need a shift in approach,” Wertheim argues. “All that implies is that we need to do even more of what we’re already doing.”

Conclusion

The COVID-19 pandemic demonstrated that viral mutations may drastically alter a pathogen’s infectiousness and illness severity.

A new study from the University of Oxford has discovered a new version of HIV, the AIDS-causing virus, that is possibly more contagious and might have a more significant impact on the immune system.

People May Ask

Q- What exactly is an HIV variant?

A- The new HIV variant produces sickness twice as quickly as the previous one.

Q- What is the cause of HIV Variant?

A- Due to the combined activities of error-prone reverse transcriptase, recombination, as well as short generation durations, the human immunodeficiency virus (HIV) develops fast, resulting in substantial viral diversity both within and across hosts.

Q- What distinguishes the HIV virus from other viruses?

A- These mutant Vif proteins were shown to be incapable of influencing viral infectivity after functional investigation. The distinctive properties of HIV-1 Vif include the low steady-state expression and the existence of truncated forms, as discussed above.

Disclaimer

The opinions presented in this article should not be regarded as a replacement for medical advice. For more information, please contact your treating physician.

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