2 Major Types of Uterine Cancer, Complete Report

The most frequent types of uterine cancer impacting the female reproductive system, which develops in the uterus or womb. As per the American Cancer Society (ACS), 65,950 cases reported of cancer are predicted to be detected in the U. S. in 2022, with the majority of cases occurring in women who have reached menopause. It is most commonly diagnosed at the age of 60.

uterine cancer

Types of Uterine Cancer

2 Major Types of Uterine Cancer, Complete Report - 1
2 Major Types of Uterine Cancer, Complete Report - 2

Endometrial cancer

Adenocarcinomas of the endometrium account for more than 80percent of all endometrial cancers.

2 Major Types of Uterine Cancer, Complete Report - 3

Serous adenocarcinoma

Cancer has a higher chance of spreading to the lymph nodes and other parts of the body.

Adenosquamous carcinoma

Rare cancer that borders the outer layer of the uterus, similar to endometrial adenocarcinoma.

Uterine carcinosarcoma

Cancer cells mimic those found in endometrial cancer and sarcoma, but they are more likely to migrate to lymph nodes and other parts of the body.

Uterine sarcoma

A rare cancer of the uterine muscular layer that accounts for fewer than 4% of all malignancies. Uterine sarcomas are classified as follows:

2 Major Types of Uterine Cancer, Complete Report - 4

Uterine leiomyosarcoma

The most prevalent kind of uterine sarcoma is in the muscular wall of the uterus, which accounts for 2% of all uterine malignancies.

Endometrial stromal sarcomas

This cancer forms in the connective tissue that supports the uterus, and it accounts for fewer than 1% of all uterine malignancies. This sort of cancer, on the other hand, usually grows slowly.

Undifferentiated sarcoma 

Undifferentiated sarcoma is similar to endometrial stromal sarcoma but develops and spreads more quickly, accounting for fewer than 1% of all uterine malignancies.

Uterine cancer with primary pure squamous cell carcinoma of the endometrium is extremely rare. It’s so uncommon that no one knows how often it is; just 70 instances have been reported to the World Health Organization. Squamous cell carcinoma (SCC) is a kind of main uterine lining cancer in which squamous cells have varying degrees of differentiation.

Read Also/Montreal Firefighters’ Association calls for an increase in the list of occupational cancers

2 Major Types of Uterine Cancer, Complete Report - 5

Endometrial cancer is caused by a variety of factors

While the exact aetiology of endometrial cancer is unknown, doctors believe that alterations in the uterine lining cells are caused by a genetic mutation in the DNA. Whenever healthy cells become unusual, they usually stop proliferating and die at a predictable pace. Endometrial cancer cells proliferate and divide uncontrolled when their DNA is altered, resulting in a mass or tumor.

Endometrial cancer is a disease that affects women of all ages.

Following are the most common causes of endometrial cancer

Tamoxifen is a drug used to treat breast cancer. Annually, see your doctor for a pelvic check, and report any abnormal vaginal bleeding right away.

Radiation treatment for any pelvic organs.

Experiencing more menstrual cycles.

Having more oestrogen exposure without adding progesterone.

Uterine cancer has a different set of risk factors than endometrial cancer, including

Treatment with radiation to the pelvic region 

Being African American puts you twice as frequently as white or Asian women to get uterine sarcoma.

Retinoblastoma is cancer that affects the retina.

2 Major Types of Uterine Cancer, Complete Report - 6

Following are the most prevalent signs of uterine cancer

Vaginal bleeding that is unusual


Bleeding after menopause

Vaginal discharge that is abnormal

Frequently urinating

Pain in the abdomen

Vaginal bulge or bulk

Feeling stuffed

Different forms of uterine cancer diagnoses

While symptoms may hint at what’s going on, it’s critical to receive a proper diagnosis. Endometrial cancer and uterine sarcoma are identified using particular tests that allow doctors to learn more about your uterus’s condition. The following kind of tests may be performed:

Pelvic ultrasound

The uterus, ovaries, and other pelvic organs are examined with an ultrasound probe wrapped in gel placed on your belly. If this view does not offer enough data, an ultrasound wand is inserted into the vagina.

Endometrial biopsy

A short flexible tube is inserted through the cervix into the uterus, and a little amount of uterine tissue is removed. During a pelvic exam, the test can be done. The sample is submitted to a lab for analysis to see if cancer cells are present.

Treatment options for uterine cancer


The most frequent surgical method for treating endometrial cancer is a hysterectomy. The uterus and cervix are removed during surgery, as well as lymph nodes, ovaries, and fallopian tubes. Side effects of surgical cancer therapy include bleeding and infection.

Radiation therapy

Radiation treatment kills endometrial cancer cells by bombarding them with high-energy radiation. Radiation can be delivered in the following ways:

Vaginal brachytherapy

Following surgery, a tube containing radioactive seeds is inserted into the vaginal canal. It has no effect on the bladder or the rectum in the same way that external radiation does.

External radiation

It’s like getting an X-ray. The entire radiation therapy period is brief, with 5 days of treatment per week for 4-6 weeks.

Skin changes and tiredness are possible side effects of radiation treatment


To eliminate cancer cells, systemic therapy is employed. Chemotherapy can be given as a pill or injected directly into your veins, allowing it to circulate throughout your body. The therapy is administered in cycles or rounds, with intervals in between. Several chemo medicines may be used in combination to provide the greatest results. Nausea, exhaustion, and hair loss are among of the side effects. Following therapy, these symptoms usually go away.

Hormone therapy 

The treatment, unlike menopausal hormone therapy, employs hormones or hormone-blocking medications to combat cancer.

Targeted drugs

Drugs target just cancer cells, not healthy cells, and have fewer adverse effects than chemotherapy.


Immunotherapy strengthens your body’s natural defenses against cancer cells, particularly advanced endometrial cancer.

Rare Uterine cancers

Endometrial cancer of the uterus, also known as uterine papillary serous carcinoma, is a rare kind of endometrial cancer that accounts for around 5% of all occurrences. Even when diagnosed early, it spreads quickly and is more likely to relapse after therapy than all other forms of cancer.
There are several risk factors to consider.

The uncommon type of endometrial cancer known as uterine papillary serous carcinoma (UPSC) accounts for roughly 5% of all occurrences.

Even when diagnosed early, it spreads quickly and is more likely to relapse after therapy than all other forms of cancer.

UPSC is more common in African-American and post-menopausal women, as well as it may be linked to a gene mutation.

UPSC patients are likely to have relatives who have been diagnosed with ovarian, endometrial, or pancreatic cancer.

The symptoms and diagnostic tests are similar to those for other kinds of uterine cancer.
Laparotomy, hysterectomy, radiation, targeted therapy, as well as chemotherapy are some of the UPSC therapies.

How can detect uterine cancer early?

When signs such as irregular vaginal bleeding are reported early, endometrial cancer can be discovered at an earlier stage. Almost 70% of women with uterine cancer are identified early when the disease is contained to the uterus. Unfortunately, 20% of women are detected after their disease has progressed to other organs nearby. About 10% of cancer patients are detected after the disease has progressed to other parts of the body.

Seeing your doctor on a regular basis might help you stay safe. The prognosis is substantially better if it is identified early. Uterine cancer does not have a screening test. During your yearly pelvic exam, however, your gynecologist will feel for any lumps or tumors in your uterus.

If you have symptoms or your doctor notices something unusual, he or she will order more testing.


Uterine cancer is the most frequent cancer in women’s reproductive systems, and it can have both emotional and physical consequences. Uterine cancer (also known as endometrial cancer) affects more women than cervical, ovarian, vulvar, vaginal, as well as fallopian tube cancer.

People May Ask

Q- What is the difference between the two types of uterine cancer?

A- Uterine carcinoma is a disorder in which cancerous cells develop in the uterine tissues (womb). Endometrial cancer, which is more prevalent, and uterine sarcoma, which is rare, are the two main kinds of uterine cancer.

Q- What is uterine cancer of high grade?

A- The term “high grade” refers to cancer cells that are weakly differentiated or non-differentiated.

Related Articles

0 0 votes
Article Rating
Notify of
Inline Feedbacks
View all comments
Back to top button
Would love your thoughts, please comment.x
Yoga For Eyesight How to Improve Heart Recovery Rate Grandma Home Remedies For Weight Loss